Biologists grow human-eye precursor from stem cells : Nature News & Comment
he most exciting thing is that the optic cup developed its structure without guidance from Sasai and his team.
The human eye is a complex structure — but the cues to build it come from inside the growing cells.
“The morphology is the truly extraordinary thing,” says Austin Smith, director of the Centre for Stem Cell Research at the University of Cambridge, UK. �
Until recently, stem-cell biologists had been able to grow embryonic stem-cells only into two-dimensional sheets. But over the past four years, Sasai has used mouse embryonic stem cells to grow well-organized, three-dimensional cerebral-cortex1, pituitary-gland2 and optic-cup3 tissue. His latest result marks the first time that anyone has managed a similar feat using human