Rapamycin antiaging research and overstated diabetes risks

 The first strong evidence that a drug could slow aging in mammals came out in 2009 when scientists reported that chronically feeding doses of rapamycin to mice significantly extended their average and maximum lifespans. Yet rapamycin, a drug used to help prevent rejection of transplanted organs, causes multiple side effects in people, including elevated triglycerides and cholesterol, increasing the risk of heart disease; moderate immune suppression, perhaps increasing infection risks; and low blood platelet levels, which raises the specter of dangerous bleeding. In recent years another especially surprising and troubling side effect has come to the fore: Chronically taking large doses of rapamycin induces “insulin insensitivity” in both rodents and humans, leading to rising blood sugar and potentially to type 2 diabetes.

via Rapamycin antiaging research and overstated diabetes risks.

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About Karen Saint Marie

Hi! I'm Karen Saint Marie. I have worked in the fields of health care, nutrition and mental wellness since 1991. Over the past two decades, I became aware that almost everyone is interested in how to feel better, live better and think better. The problem is, most people find it impossible to prioritize their physical and mental health while juggling family, jobs, and community projects. I have helped many individuals and small groups learn to identify, understand and implement better health and wellness practices. Wellness is a many-fold process. To begin, pick a place to start and get the process going. Being healthy in mind and body doesn't mean spending hours every day focused on healthy living. Instead, it is easier to make healthy living a natural and enjoyable part of our lives. Taking care of our minds means putting the right things in our bodies. It means pushing our minds in fun and explorative ways. Learning about the latest neuroscience and psychological research is helpful. It shows us the easiest ways to keep our brains humming along, well into our later years. Taking care of our bodies means being aware of our movements. It means making good choices for healthy foods, even when we eat out for most of our meals. It doesn't have to be hard, and, it can be a lot of fun. Living a great life doesn't have to come at a high price. It just involves knowing what is needed, and then, doing some small part of that every day. You can contact me at karen.saintmarie@gmail.com.

Posted on July 14, 2012, in Life Extension, Research. Bookmark the permalink. Leave a comment.

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