Omega-3s: Fishing for a Mechanism

Mithridates VI, king of Pontus and Armenia Minor in northern Anatolia (now Turkey) from about 120 BC to 63 BC, was a forward-thinking and perceptive individual who understood that a little bit of stress can be a good thing. Terrified of succumbing to the same fate as his father, who was assassinated by poisoning at his own banquet, Mithridates began ingesting sublethal doses of poisons to develop immunity to them, a real-life example of The Princess Bride’s Westley.

The benefit of this practice, which in modern times is known as “hormesis,” is believed to stem from the fact that in low, subtoxic amounts, poisons, toxins, and other types of stress will upregulate antioxidants and detoxification enzymes in the liver, heart, and other major organs, thereby augmenting the natural ability of the body to detoxify and protect itself against future exposure to those same toxins. Could that be what’s happening with n-3 PUFAs in the heart? Could the highly reactive oxidized products generated from PUFA oxidation cause adaptations in the heart—such as biochemical/biophysical alterations in membranes and the upregulation of cardio-protective genes—that subsequently protect the vital organ against disease and stress?

via Omega-3s: Fishing for a Mechanism | The Scientist Magazine®.

via Omega-3s: Fishing for a Mechanism | The Scientist Magazine®.

Advertisements

About Karen Saint Marie

Hi! I'm Karen Saint Marie. I have worked in the fields of health care, nutrition and mental wellness since 1991. Over the past two decades, I became aware that almost everyone is interested in how to feel better, live better and think better. The problem is, most people find it impossible to prioritize their physical and mental health while juggling family, jobs, and community projects. I have helped many individuals and small groups learn to identify, understand and implement better health and wellness practices. Wellness is a many-fold process. To begin, pick a place to start and get the process going. Being healthy in mind and body doesn't mean spending hours every day focused on healthy living. Instead, it is easier to make healthy living a natural and enjoyable part of our lives. Taking care of our minds means putting the right things in our bodies. It means pushing our minds in fun and explorative ways. Learning about the latest neuroscience and psychological research is helpful. It shows us the easiest ways to keep our brains humming along, well into our later years. Taking care of our bodies means being aware of our movements. It means making good choices for healthy foods, even when we eat out for most of our meals. It doesn't have to be hard, and, it can be a lot of fun. Living a great life doesn't have to come at a high price. It just involves knowing what is needed, and then, doing some small part of that every day. You can contact me at karen.saintmarie@gmail.com.

Posted on November 1, 2012, in Diet, Heart Disease, Inflammation, Life Extension, Nutrition, Nutritive Medicine, Research and tagged , , , . Bookmark the permalink. Leave a comment.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: